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Special Issue Title:

Balanitis Xerotica Obliterans

Deadline for manuscript submissions: 20 July 2022

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Special Issue Editor

  • Guest Editor

    Prof. Carmelo Romeo, MDE-MailWebsite

    Department of Human Pathology of Adult and Childhood “Gaetano Barresi”, Unit of Pediatric Surgery, University of Messina, Messina, Italy

    Interests: Biomelecular mechanisms of damage in balanitis xerotica obliterans and possible new therapeutic strategies; Effects of CO2 on in vitro model of neuroblastoma cells

Special Issue Information

Dear Colleagues,

Lichen sclerosus (LS) is a chronic inflammatory skin disease characterised by sclerotic, pruritic lesions that primarily affect the anogenital region. LS causes significant morbidity in patients of all genders and ages. The incidence of LS in boys is not well documented, however the most common age for affected boys is 8 years (range 1–16). Routine diagnosis can be made clinically, but histological study remains crucial to rule out important differential diagnoses. Several genetic, physiological and environmental factors contribute to the pathological process seen in LS. The etiology and the precise molecular mechanisms underlying this disease are nevertheless unknown. 

In boys, the lesions generally affect the foreskin and glans (balanitis xerotica obliterans, BXO), leading to phimosis and potential meatal stenosis. The main symptom in adult males is dyspareunia, resulting in a significant impact on quality of life. Complications include urinary and sexual dysfunction, genital scarring, and the development of malignant neoplastic diseases in adult life. Clinical studies indicate that 4.5-8.4% of male patients with LS will develop squamous cell carcinoma of the penis (PSCC).

Circumcision is regarded as the definitive management for BXO in boys. Studies with supplemental medical therapies such as topical steroids, immune modulators, intra-lesional triamcinolone, ozonated olive oil and carbon dioxide laser have been described in both adults and children with BXO. 

Several matters relating to both the pathogenetic mechanisms and the treatment options for LS remain unresolved. This special issue aims to address the various topics that are still being debated. 

Prof. Carmelo Romeo

Guest Editor


Lichen sclerosus; Balanitis xerotica obliterans; Circumcision; Anti-Inflammatory agents; Tissue regeneration; Phimosis; Squamous cell carcinoma of the penis

Manuscript Submission Information

Submissions will be accepted on a rolling basis and reviewed by experts in the field. Rapid peer review and prompt editorial decisions will ensure that quality manuscripts are published on time. The manuscript has not already been published or submitted elsewhere (except conference proceedings papers). If similar work has been published or submitted elsewhere, you must provide a copy of the submitted manuscript. You may not submit your manuscript elsewhere while it is under consideration at the Journal of Men's Health. All manuscripts undergo thorough double-blind peer-review. To check the suitability of the special issue for publishing your manuscript, please read the journal's aims and scope and read or download the guide for authors. You may also send a brief abstract of your work (about 100 words) to the Editorial Office at A guide for authors and other relevant information for manuscript submission is available on the Instructions for Authors page.

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Authors who feel that their manuscript may benefit from additional academic writing or language editing support before submission are strongly encouraged to use academic editing services.

Article Processing Charges (APC)

All manuscripts submitted to the Journal of Men's Health are assessed according to the journal standard editorial criteria. If accepted for publication, an Article Processing Charge of 1250 USD applies.

Type of Articles: Original Research, Review, Mini-Review, Systematic Review, Short Communication, Case Report, Letter to the Editor, Commentary, Rapid Report, Meeting Report, News and Views

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