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Original Research

Open Access


  • Wang Xi1
  • Dong Gan2
  • Shao Cuihua3
  • Wang Peitao4

1International Hospital Preparatory Office, The Affiliated Hospital of Qingdao University, Shandong, China

2Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China

3Department of Obstetrics, The Affiliated Hospital of Qingdao University, Shandong, China

4Department of Andrology, The Affiliated Hospital of Qingdao University, Shandong, China

DOI: 10.15586/jomh.v16i3.255 Vol.16,Issue 3,July 2020 pp.19-28

Published: 16 July 2020

*Corresponding Author(s): Wang Peitao E-mail:

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The aim of this study was to assess the awareness of fertility protection among male patients and their healthcare providers in the treatment process of cancer.


In a cross-sectional study, we applied a questionnaire survey among patients and healthcare providers who were selected randomly: the physician group consisted of oncologists and hematologists, and the patient group included participants with cancer from 15 to 45 years old, who were recruited from hos-pitals in Qingdao. Meanwhile, data from male cancer patients, who received sperm cryopreservation in our hospital, were also analyzed.


Data collected from healthcare provider group showed that more than 80% of clinicians warned patients of the fertility impairment along with chemotherapy or other treatments, whereas a few clini-cians recommended specific methods for reproductive protection to patients with special attention be paid to the follow-up fertility result. In patient group, more than 50% indicated they would accept the loss of fertility caused by cancer therapies. The rate of awareness of sperm cryopreservation, as an effective way of reproductive protection, was low among both physician and patient groups. In the past 3 years, only 63 samples of semen from 54 cancer patients were cryopreserved in our hospital. 


The awareness of reproductive protection in both physicians and cancer patients was not satisfied in Qingdao, China, and this finding indicates a need for comprehensive health education and practical protocols for both patients and healthcare providers in terms of reproductive protection for male patients with cancers.


cancer; fertility impairment; reproductive protection; sperm cryopreservation

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