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Original Research

Open Access


  • Farshad Pourmalek1,2
  • S. Larry Goldenberg1
  • Kendall Ho3
  • Sean C. Skeldon4
  • David M. Patrick2

1Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

2School of Population and Public Health, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

3Department of Emergency Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

4Department of Family & Community Medicine, Faculty of Medicine, University of Toronto, Ontario, Canada

DOI: 10.22374/1875-6859.13.1.2 Vol.13,Issue 1,May 2017 pp.9-18

Published: 25 May 2017

*Corresponding Author(s): S. Larry Goldenberg E-mail:

PDF (1.43 MB)


Background and Objective:

To facilitate the engagement of men in the evaluation of their own health status and risk of disease, we have developed and validated the Canadian Men’s Health Foundation’s self-risk assessment tool (“You Check”). In a single questionnaire, the “You Check” tool estimates the 10-year risk for myocardial infarction (MI), diabetes type 2 (DM), osteoporosis (OS), erectile dysfunction (ED), and low testosterone (LT). Additionally, the tool provides the user with his risk-factor profi le for prostate cancer and his current risk of depression (using the Center for Epidemiologic Studies Depression scale).

 Materials and Methods: 

Known risk factors for each disease were collated, the questionnaire designed, and risk scores for each dis-ease were assigned by clinical experts. A risk formula was developed using the sum of risk scores divided by their own range. We validated the risk models with case-control data from a retrospective review of 400 outpatient records from 4 Vancouver family practice clinics. Maximal correct classifi cation proportions were determined and used as thresholds for categorization of risk to low, medium, or high categories.


For DM, sensitivity and specifi city were 0.86 and 0.96 respectively and the Area Under Curve was 0.88 (95% Confi dence Interval [CI] 0.81-0.94). For MI these values were 0.70 and 0.93, and 0.75 (0.65-0.85); for LT 0.70 and 0.90 and 0.75 (0.66–0.84); for OS 0.70 and 0.86 and 0.70 (0.61–0.80); and for ED 0.42 and 0.96 and 0.66 (0.58–0.75).


This is the fi rst comprehensive men’s health self-risk assessment tool for 7 important diseases. Moderate internal validity was demonstrated for 5 diseases, meeting the public health objectives of “You Check” which is now in the public domain and under appropriate monitoring and evaluation (


men’s health, risk assessment, risk model, internal validation

Cite and Share

Farshad Pourmalek,S. Larry Goldenberg,Kendall Ho,Sean C. Skeldon,David M. Patrick. DEVELOPMENT AND CASE-CONTROL VALIDATION OF THE CANADIAN MEN’S HEALTH FOUNDATION’S SELF RISK-ASSESSMENT TOOL: “YOU CHECK”. Journal of Men's Health. 2017. 13(1);9-18.


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