Analysis on risk factors and characteristics of coronary angiography in young men with CHD

To examine the risk factors associated with coronary heart disease (CHD) in young males and assess the distinctive features of coronary angiography (CAG). The clinical data of 266 young men who underwent CAG were collected and categorized into CHD group and control group based on the results of CAG. Binary logistic regression was used to analyze the risk factors for CHD in young men. Additionally, we selected 112 middle-aged and elderly men with CHD to form the middle-aged and elderly case group. We then compared the CAG characteristics and short-term prognosis with those of the CHD group. The CAG examination revealed a CHD detection rate of 42.11%(112/266) in young men, with 154 patients (57.89%) exhibiting no significant stenosis. Notably, the CHD group had higher rates of family history, hypertension and an elevated triglyceride glucose product (TyG) index (p < 0.05), along with a shorter duration of sleep compared to the control group (p < 0.05). Binary logistic regression analysis confirmed family history of CHD, hypertension, TyG index ≥8.83, and insufficient sleep duration as risk factors for CHD in young men. Additionally, the CHD group had a higher proportion of single-vessel coronary artery disease compared to the middle-aged and elderly case group (p < 0.05). Conversely, the middle-aged and elderly case group had a higher proportion of multi-vessel coronary artery disease, left circumflex artery involvement, and right coronary artery involvement (p < 0.05). The CHD group exhibited a lower overall incidence of major adverse cardiovascular events compared to the middle-aged and elderly case group (p < 0.05). The incidence of CHD in young men is closely associated with a family history of CHD and hypertension. High TyG index and insufficient sleep duration may also increase the risk of CHD.

CHD; Youth; Male; Risk factors; Imaging characteristics; CAG

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