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Original Research

Open Access

Analysis of risk factors for benign prostate enlargement with prostate calcification

  • Xiaoling Chen1
  • Yanzhi Han2,*,

1Department of Health Management Physical Examination Center, The Fifth Affiliated Hospital Sun Yat-sen University, 519000 Zhuhai, Guangdong, China

2Department of Gastroenterology, The Fifth Affiliated Hospital Sun Yat-sen University, 519000 Zhuhai, Guangdong, China

DOI: 10.22514/jomh.2024.014 Vol.20,Issue 1,January 2024 pp.107-113

Submitted: 27 September 2023 Accepted: 28 November 2023

Published: 30 January 2024

*Corresponding Author(s): Yanzhi Han E-mail:


The occurrence of benign prostatic hyperplasia (BPH) accompanied by calcification can reduce the quality of life and treatment effectiveness of patients. This study focuses on middle-aged and elderly patients in physical examination centers, and divides them into a control group and a study group based on their condition. By comparing the general information and serum indicators of the subjects, descriptive analysis methods are used to analyze the risk factors for prostate hyperplasia accompanied by calcification. Among 700 male physical examinations, there were 305 patients with benign prostate enlargement, with a prevalence rate of 43.57%. There were 290 patients with prostate calcification, accounting for 41.43%. Among them, there were 203 patients with prostate calcification in BPH, accounting for 66.56%. Multivariate logistic regression analysis showed that age, education and culture, diabetes, hypertension, uric acid (UA) and blood urea nitrogen (BUN) are independent risk factors for prostate calcification, while height is the protective factor. The prevalence rate of BPH and BPH with prostate calcification is high in middle-aged and elderly men. Although the cause of calcification is still unclear, age, education, occupation, diabetes, hypertension, UA, BUN and prostate-specific antigen (PSA) indicators are closely related to the disease. Therefore, early intervention should be carried out according to the above risk factors to prevent the occurrence of the disease as soon as possible.


Benign prostatic enlargement; Prostate calcification; Risk factor analysis

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Xiaoling Chen,Yanzhi Han. Analysis of risk factors for benign prostate enlargement with prostate calcification. Journal of Men's Health. 2024. 20(1);107-113.


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