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Original Research

Open Access

The efficacy of transurethral holmium laser enucleation of the prostate (HoLEP) in the preservation of the urethral ridge in the treatment of prostatic hyperplasia in patients aged 75 years or less

  • Rongjin Fang1
  • Qinglong Wu1,*,
  • Chao Li1
  • Nanhua Li2
  • Yiliang Huang1
  • Songtao Zhao1

1Department of Urology, Xiamen Haicang Hospital, 361000 Xiamen, Fujian, China

2Department of Rehabilitation Medicine, Xiamen Third Hospital, 361000 Xiamen, Fujian, China

DOI: 10.22514/jomh.2024.088 Vol.20,Issue 6,June 2024 pp.35-41

Submitted: 13 October 2023 Accepted: 21 November 2023

Published: 30 June 2024

*Corresponding Author(s): Qinglong Wu E-mail: gohking15@163.com

Abstract

To evaluate the efficacy of Transurethral holmium laser enucleation of the prostate (HoLEP) with preservation of the urethral ridge in the treatment of benign prostatic hyperplasia (BPH) in patients aged 75 years or less. We conducted retrospective analysis of clinical data acquired from 80 patients aged 75 years or less with BPH. We also included 30 cases of HoLEP with preservation of the “urethral ridge” (the modified group) and 50 cases of HoLEP (the control group). Analysis showed that there were no significant differences in operation time (59.5 (55.0, 66.0) min vs. 57.0 (52.5, 64.3) min), the weight of prostate tissue removed (45.4 ± 13.5 vs. 47.7 ± 15.2 grams), hemoglobin drop (1.5 ± 0.4 grams per liter vs. 1.4 ± 0.3 grams per liter), the time of postoperative bladder irrigation (21.0 (19.8, 23.3) h vs. 21.0 (19.0, 23.2) h), postoperative indwelling catheter time (4.0 (3.0, 4.0) d vs. 4.0 (3.0, 4.0) d) and postoperative hospitalization time (5.0 (4.0, 5.0) d vs. 5.0 (4.0, 5.0) d) between the two groups (all p > 0.05). However, there was a significant difference in the immediate postoperative urinary control rate (93.3% (28/30) vs. 76% (38/50), p < 0.05) and the incidence of retrograde ejaculation (5 cases (16.7%) vs. 19 cases (38%), p < 0.05) between the two groups. In addition, we identified significant differences in the International Prostate Symptom Score (IPSS), quality-of-life score (QoL), maximum urinary flow rate (Qmax), International Index of Erectile Function score (IIEF-5), and postvoid residual volume (PVR) intragroup comparison (all p < 0.05). The efficacy of HoLEP with preservation of the “urethral ridge” in the treatment of BPH was found to be comparable to that of conventional two-lobe HoLEP but can improve the rate of immediate urinary control and reduce the incidence of retrograde ejaculation.


Keywords

Holmium laser enucleation of the transurethral prostate; Benign prostatic hyperplasia (BPH); Urethral ridge; Immediate urinary control; Retrograde ejaculation


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Rongjin Fang,Qinglong Wu,Chao Li,Nanhua Li,Yiliang Huang,Songtao Zhao. The efficacy of transurethral holmium laser enucleation of the prostate (HoLEP) in the preservation of the urethral ridge in the treatment of prostatic hyperplasia in patients aged 75 years or less. Journal of Men's Health. 2024. 20(6);35-41.

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