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Case Report

Open Access Special Issue

Malignant biphasic mesothelioma of the tunica vaginalis testis: a case report

  • Lennart Kühnke1,†
  • Melisa Hoshaber1,†
  • Stefan Steurer2
  • Philipp Schriefer3
  • Margit Fisch1
  • Dejan Filipas1
  • Michael Hartmann1
  • Christoph Seidel4
  • Armin Soave1,*,

1Department of Urology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany

2Department of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany

3Urology Practice Buxtehude, 21614 Buxtehude, NI, Germany

4Department of Oncology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany

DOI: 10.22514/jomh.2025.136 Vol.21,Issue 11,November 2025 pp.64-67

Submitted: 17 February 2025 Accepted: 25 August 2025

Published: 30 November 2025

*Corresponding Author(s): Armin Soave E-mail: a.soave@uke.de

† These authors contributed equally.

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Abstract

Background: Malignant mesothelioma of the tunica vaginalis testis (MMTVT) is a rare malignancy often presenting with non-specific symptoms, leading to diagnostic challenges. Case: We report the case of a 36-year-old patient initially presenting with hydrocele-like symptoms, highlighting the complexities of MMTVT diagnosis and management. Furthermore, while asbestos exposure is a recognized risk factor, this case lacked a significant history of such exposure, suggesting the need to explore alternative etiological factors. Conclusions: Radical orchiectomy remains the standard treatment, yet the role of adjuvant therapies is not yet well-defined due to the rarity of the disease.


Keywords

Malignant mesothelioma of the tunica vaginalis testis (MMTVT); Asbestos exposure; Hydrocele; Magnetic resonance imaging; Computertomography scan; Positron emission tomography CT; β-human chorionic gonadotropin (β-HCG); Alpha feto-protein (AFP); On-bloc hemiscrotectomy


Cite and Share

Lennart Kühnke,Melisa Hoshaber,Stefan Steurer,Philipp Schriefer,Margit Fisch,Dejan Filipas,Michael Hartmann,Christoph Seidel,Armin Soave. Malignant biphasic mesothelioma of the tunica vaginalis testis: a case report. Journal of Men's Health. 2025. 21(11);64-67.

URL:

https://www.jomh.org/articles/10.22514/jomh.2025.136

References

[1] Wagner JC, Sleggs CA, Marchand P. Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province. British Journal of Industrial Medicine. 1960; 17: 260–271.

[2] Iczkowski KA. Germ cell neoplasms of the testis: update for 2022. Seminars in Diagnostic Pathology. 2023; 40: 2–21.

[3] Barbera V, Rubino M. Papillary mesothelioma of the tunica vaginalis. Cancer. 1957; 10: 183–189.

[4] Segura-González M, Urias-Rocha J, Castelán-Pedraza J. Malignant mesothelioma of the tunica vaginalis: a rare neoplasm—case report and literature review. Clinical Genitourinary Cancer. 2015; 13: e401–e405.

[5] Plas E, Riedl CR, Pflüger H. Malignant mesothelioma of the tunica vaginalis testis: review of the literature and assessment of prognostic parameters. Cancer. 1998; 83: 2437–2446.

[6] Butnor KJ, Pavlisko EN, Sporn TA, Roggli VL. Mesothelioma of the tunica vaginalis testis. Human Pathology. 2019; 92: 48–58.


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