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Case Report

Open Access Special Issue

Prostatic signet-ring adenocarcinoma: A case report

  • Ali Al Khader1,2,*,
  • Esra Nsour2
  • Taleb Al Edwan3

1Department of Pathology and Forensic Medicine, Faculty of Medicine, Al-Balqa Applied University, 19117 Al-Salt, Jordan

2Department of Pathology, Al Hussein Salt Hospital, Ministry of Health, 19117 Al-Salt, Jordan

3Department of Urology, Al-Hussein Salt Hospital, Ministry of Health, 19117 Al-Salt, Jordan

DOI: 10.31083/j.jomh1804090 Vol.18,Issue 4,April 2022 pp.1-3

Submitted: 26 August 2021 Accepted: 11 October 2021

Published: 30 April 2022

(This article belongs to the Special Issue Therapy and prognosis of metastatic prostate cancer)

*Corresponding Author(s): Ali Al Khader E-mail: ali.alkhader@bau.edu.jo

Abstract

Background: Prostatic signet-ring adenocarcinoma is a rare histological variant of prostate cancer. The tumor is characterized by an aggressive clinical course. Methods: Herein we present the case of a 78-year-old man with obstructive urinary symptoms and elevated serum prostate specific antigen. Transurethral resection of the prostate was performed. Results: Histologically, a tumor that was mainly composed of signet ring cells was identified. The tumor cells were positive for alcian blue special stain. Another Gleason 4 adenocarcinoma component was identified. The patient received hormonal therapy. A favorable response was documented at 8 months of follow up. Conclusions: Ruling out another primary site of origin, such as the gastrointestinal tract, is mandatory, and a more aggressive management plan should be put in mind.


Keywords

Carcinoma; Prostate; Signet ring cell

Cite and Share

Ali Al Khader,Esra Nsour,Taleb Al Edwan. Prostatic signet-ring adenocarcinoma: A case report. Journal of Men's Health. 2022. 18(4);1-3.

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