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Original Research

Open Access

Influence of antibacterial mouthwash on post-exercise hypotension

  • Yerim Choi1
  • Min-gyeong Kang2
  • Seung Kyum Kim1,2,*,

1Convergence Institute of Biomedical Engineering and Biomaterials, Seoul National University of Science and Technology, 01811 Seoul, Republic of Korea

2Department of Sports Science, Seoul National University of Science and Technology, 01811 Seoul, Republic of Korea

DOI: 10.31083/j.jomh1805117 Vol.18,Issue 5,May 2022 pp.1-7

Submitted: 19 October 2021 Accepted: 21 December 2021

Published: 31 May 2022

*Corresponding Author(s): Seung Kyum Kim E-mail:


Background: Acute exercise induces a blood pressure (BP) reduction that lasts minutes to hours, which is called post-exercise hypotension (PEH). Accumulating data suggest that oral bacteria play a role in BP regulation by contributing to nitric oxide production, implying that antibacterial mouthwash (AM) could affect PEH. Therefore, this study aimed to investigate the effects of an AM on post-exercise changes in BP and arterial stiffness index (ASI). Methods: Ten healthy young men completed two treadmill exercises at moderate intensity. After exercise, the subjects rinsed their mouth for 1 min with AM or nitrite-free water at 5, 35, 65, and 95 min during the recovery period. BP and ASI were assessed at 0, 10, 20, 30, 60, 90, and 120 min during the recovery period. Heart rate (HR) and blood lactate (BL) were also measured. Results: As expected, PEH occurred showing a decrease in the systolic, diastolic, and mean arterial pressures after exercise in the placebo group. The ASI also decreased after exercise in the placebo group. However, these BP-lowering effects of exercise were significantly diminished by AM, particularly at the later times of the recovery period. In addition, there was a difference between the treatments in ASI changes, but not in HR and BL changes. Conclusion: These findings demonstrate that AM usage after exercise can attenuate the beneficial effects of exercise on BP and the vasculature.


post-exercise hypotension; antibacterial mouthwash; arterial stiffness

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Yerim Choi,Min-gyeong Kang,Seung Kyum Kim. Influence of antibacterial mouthwash on post-exercise hypotension. Journal of Men's Health. 2022. 18(5);1-7.


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