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Original Research

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Self-reported Physical Health as a Mediator of the Effects of BMI on Depression among People with Multiple Chronic Conditions

  • Cheng Cheng1,*,
  • Jie Bai2

1School of Nursing, Shanghai Medical College, Fudan University, 200032 Shanghai, China

2IVF Center, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, 201204 Shanghai, China

DOI: 10.31083/j.jomh1809183 Vol.18,Issue 9,September 2022 pp.1-5

Published: 22 September 2022

*Corresponding Author(s): Cheng Cheng E-mail:


Background: The current study examined whether the association between body mass index (BMI) and symptoms of depression is mediated by self-reported physical health among Chinese people with multiple chronic conditions (MCCs). Methods: This was a secondary analysis based on a previous cross-sectional survey using the Hospital Anxiety and Depression Scale (HADS) and Short Form-12 (SF-12). A convenience sample of Chinese people with MCCs (n = 351) was recruited and a mediation effect model using SPSS PROCESS was employed. Results: The results showed that self-reported physical health acted as a full mediator in the association between BMI and depression only for men with MCCs. Conclusions: The findings of this study suggest that decreased physical health should be of primary importance in the management of MCCs. Further intervention addressing weight control could be a strategy of particular interest for improving the mental health of people with MCCs.


body mass index; depression; multiple chronic conditions; obesity; physical health

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Cheng Cheng,Jie Bai. Self-reported Physical Health as a Mediator of the Effects of BMI on Depression among People with Multiple Chronic Conditions. Journal of Men's Health. 2022. 18(9);1-5.


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