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Original Research

Open Access

A Self-Guided Lifestyle Intervention for Young Men: Findings from the ACTIVATE Randomized Pilot Trial

  • Jean M. Reading1,*,
  • Melissa M. Crane2
  • Kellie Carlyle1
  • Robert A. Perera3
  • Jessica Gokee LaRose1

1Department of Health Behavior and Policy, Virginia Commonwealth University School of Medicine, Richmond, VA 23219, USA

2Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA

3Department of Biostatistics, Virginia Commonwealth University School of Medicine, Richmond, VA 23219, USA

DOI: 10.31083/j.jomh1809191 Vol.18,Issue 9,September 2022 pp.1-8

Published: 22 September 2022

*Corresponding Author(s): Jean M. Reading E-mail:


Background: Young men are at high risk for developing obesity-related health complications, yet are markedly underrepresented in lifestyle interventions. This pilot study examined the feasibility and preliminary efficacy of a lifestyle intervention (self-guided + health risk messaging) targeting young men. Methods: 35 young men (Age = 29.3 ± 4.27; BMI = 30.8 ± 4.26; 34% racial/ethnic minority) were randomly assigned to the intervention or delayed treatment control. The intervention (ACTIVATE) included 1 virtual group session, digital tools (wireless scale, self-monitoring app), access to self-paced content via a secure website, and 12 weekly texts to reinforce health risk messaging. Fasted objective weight was assessed remotely at baseline and 12-weeks. Perceived risk was assessed via survey at baseline, 2-week, and 12-week. T-tests were used to compare weight outcomes between arms. Linear regressions examined the association between percent weight change and perceived risk change. Results: Recruitment was successful as evidenced by 109% of target enrollment achieved in a 2-month period. Retention was 86% at 12 weeks, with no differences by arm (p = 0.17). Participants in the intervention arm experienced modest weight loss at 12 weeks, whereas slight gains were observed in the control arm (–1.6% ± 2.5 vs. +0.31% ± 2.8, p = 0.04). Change in perceived risk was not associated with change in percent weight (p > 0.05). Conclusions: A self-guided lifestyle intervention showed initial promise for weight management among young men, but these findings are limited by small sample size. More research is needed to bolster weight loss outcomes while retaining the scalable self-guided approach. Clinical Trial Registration: NCT04267263 (


behavioral interventions; male-targeted; weight loss; health risk messages; low intensity; obesity

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Jean M. Reading,Melissa M. Crane,Kellie Carlyle,Robert A. Perera,Jessica Gokee LaRose. A Self-Guided Lifestyle Intervention for Young Men: Findings from the ACTIVATE Randomized Pilot Trial. Journal of Men's Health. 2022. 18(9);1-8.


[1] Hales CM, Carroll MD, Fryar CD, Ogden CL. Prevalence of Obesity and Severe Obesity Among Adults: United States, 2017–2018. NCHS Data Brief. 2020; 1–8.

[2] Dixon JB. The effect of obesity on health outcomes. Molecular and Cellular Endocrinology. 2010; 316: 104–108.

[3] Lin C, Chang Y, Cheng T, Lo K, Liu S, Yeh TL. The association between metabolically healthy obesity and risk of cancer: A sys-tematic review and meta-analysis of prospective cohort studies. Obesity Reviews. 2020; 21: e13049.

[4] Heron MP. Deaths: Leading Causes for 2016. Prevention CfDCa: Washington, D.C. 2018.

[5] Bodenlos JS, Gengarelly K, Smith R. Gender differences in freshmen weight gain. Eating Behaviors. 2015; 19: 1–4.

[6] Eicher-Miller HA, Fulgoni VL, Keast DR. Energy and Nutrient Intakes from Processed Foods Differ by Sex, Income Status, and Race/Ethnicity of us Adults. Journal of the Academy of Nutri-tion and Dietetics. 2015; 115: 907–918.e6.

[7] Jakicic JM, King WC, Marcus MD, Davis KK, Helsel D, Rick-man AD, et al. Short-term weight loss with diet and physical activity in young adults: the IDEA study. Obesity. 2015; 23: 2385–2397.

[8] Svetkey LP, Batch BC, Lin P, Intille SS, Corsino L, Tyson CC, et al. Cell phone intervention for you (CITY): a randomized, controlled trial of behavioral weight loss intervention for young adults using mobile technology. Obesity. 2015; 23: 2133–2141.

[9] Crane MM, Lutes LD, Ward DS, Bowling JM, Tate DF. A ran-domized trial testing the efficacy of a novel approach to weight loss among men with overweight and obesity. Obesity. 2015; 23: 2398–2405.

[10] Rounds T, Crane M, Harvey J. The Impact of Incentives on Weight Control in Men: a Randomized Controlled Trial. Amer-ican Journal of Men’s Health. 2020; 14: 1557988319895147.

[11] Eisenhauer CM, Brito F, Kupzyk K, Yoder A, Almeida F, Beller RJ, et al. Mobile health assisted self-monitoring is acceptable for supporting weight loss in rural men: a pragmatic randomized controlled feasibility trial. BMC Public Health. 2021; 21: 1568.

[12] Dombrowski SU, McDonald M, van der Pol M, Grindle M, Avenell A, Carroll P, et al. Game of Stones: feasibility ran-domised controlled trial of how to engage men with obesity in text message and incentive interventions for weight loss. BMJ Open. 2020; 10: e032653.

[13] Realmuto L, Kamler A, Weiss L, Gary-Webb TL, Hodge ME, Pagán JA, et al. Power Up for Health-Participants’ Perspectives on an Adaptation of the National Diabetes Prevention Program to Engage Men. American Journal of Men’s Health. 2018; 12: 981–988.

[14] LaRose JG, Guthrie KM, Lanoye A, et al. A mixed methods approach to improving recruitment and engagement of emerging adults in behavioural weight loss programs. Obesity science & practice. 2016; 2: 341–354.

[15] O’Connor EA, Evans CV, Rushkin MC, Redmond N, Lin JS. Behavioral Counseling to Promote a Healthy Diet and Phys-ical Activity for Cardiovascular Disease Prevention in Adults with Cardiovascular Risk Factors: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. The Journal of the American Medical Association. 2020; 324: 2076–2094.

[16] Ashton LM, Hutchesson MJ, Rollo ME, Morgan PJ, Thompson DI, Collins CE. Young adult males’ motivators and perceived barriers towards eating healthily and being active: a qualitative study. International Journal of Behavioral Nutrition and Physical Activity. 2015; 12: 93.

[17] Morgan PJ, Callister R, Collins CE, Plotnikoff RC, Young MD, Berry N, et al. The SHED-it Community Trial: a Randomized Controlled Trial of Internet- and Paper-Based Weight Loss Pro-grams Tailored for Overweight and Obese Men. Annals of Be-havioral Medicine. 2013; 45: 139–152.

[18] Young M, Drew R, Kay-Lambkin F, Collins CE, Callister R, Kelly BJ, et al. Impact of a self-guided, eHealth program tar-geting weight loss and depression in men: A randomized trial. Journal of Consult Clinical Psychology. 2021; 89: 682–694.

[19] LaRose J G, Gorin A A, Clarke M M, et al. Beliefs about weight gain among young adults: potential challenges to prevention. Obesity. 2011; 19: 1901–1904.

[20] Gregory CO, Blanck HM, Gillespie C, Maynard LM, Serdula MK. Perceived health risk of excess body weight among over-weight and obese men and women: Differences by sex. Preven-tive Medicine. 2008; 47: 46–52.

[21] Let’s Move! Obama White House. 2021. Avaliable at: (Accessed: 25 August 2021).

[22] Zonouzy VT, Niknami S, Ghofranipour F, Montazeri A. An ed-ucational intervention based on the extended parallel process model to improve attitude, behavioral intention, and early breast cancer diagnosis: a randomized trial. International Journal of Women’s Health. 2018; 11: 1–10.

[23] Witte K. Putting the fear back into fear appeals: the extended parallel process model. Communication Monographs. 1992; 59: 329–349.

[24] Gharlipour Z, Hazavehei SM, Moeini B, Nazari M, Beigi AM, Tavassoli E, et al. The effect of preventive educational program in cigarette smoking: Extended Parallel Process Model. Journal of Education and Health Promotion. 2015; 4: 4.

[25] Aliyari S, Hosseini-Amiri M, Zareiyan A, Dabbagh-Moghadam A. The effects of extended parallel process model on obese sol-diers’ knowledge, attitudes, and practices about obesity manage-ment: a randomized controlled clinical trial. Iranian Journal of Nursing and Midwifery Research. 2018; 23: 458–464.

[26] Hatchell AC, Bassett-Gunter RL, Clarke M, Kimura S, Latimer-Cheung AE. Messages for men: the efficacy of EPPM-based messages targeting men’s physical activity. Health Psychology. 2013; 32: 24–32.

[27] Orkin AM, Gill PJ, Ghersi D, Campbell L, Sugarman J, Emsley R, et al. Guidelines for Reporting Trial Protocols and Completed Trials Modified Due to the COVID-19 Pandemic and Other Extenuating Circumstances: The CONSERVE 2021 Statement. The Journal of the American Medical Association. 2021; 326: 257–265.

[28] Diabetes Prevention Program Research G. The Diabetes Preven-tion Program (DPP): description of lifestyle intervention. Dia-betes Care. 2002; 25: 2165–2171.

[29] Burke LE, Wang J, Sevick MA. Self-Monitoring in Weight Loss: a Systematic Review of the Literature. Journal of the American Dietetic Association. 2011; 111: 92–102.

[30] Tate DF, Lytle L, Polzien K, Diamond M, Leonard KR, Jakicic JM, et al. Deconstructing Weight Management Interventions for Young Adults: Looking Inside the Black Box of the EARLY Consortium Trials. Obesity. 2019; 27: 1085–1098.

[31] Reading J M, LaRose J G. Exercise preferences among emerging adults: Do men and women want different things? Journal of American College Health. 2020; 1–5.

[32] Witte K. Predicting Risk Behaviors: Development and Valida-tion of a Diagnostic Scale. Journal of Health Communication. 1996; 1: 317–341.

[33] Jensen MD, Ryan DH, Apovian CM, Ard JD, Comuzzie AG, Donato KA, et al. 2013 AHA/ACC/TOS Guideline for the Man-agement of Overweight and Obesity in Adults. Circulation. 2014; 129: S102–S138.

[34] Ashton LM, Morgan PJ, Hutchesson MJ, Rollo ME, Collins CE. Feasibility and preliminary efficacy of the ‘HEYMAN’ healthy lifestyle program for young men: a pilot randomised controlled trial. Nutrition Journal. 2017; 16: 2.

[35] Pagoto SL, Schneider KL, Oleski JL, Luciani JM, Bodenlos JS, Whited MC. Male Inclusion in Randomized Controlled Trials of Lifestyle Weight Loss Interventions. Obesity. 2012; 20: 1234–1239.

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