Effect of Topical Sports Cream Containing Cymbopogon schoenanthus on Acute Recovery Markers Following Exercise-Induced Muscle Fatigue in Competitive Athletes: A Pilot Study

Background: Muscle fatigue following high-intensity or repetitive training causes reduced muscle strength, restriction of blood flow, and increased muscle pain. The application of topical sports cream (TSC) as a recovery method has recently gained attention. However, few studies have investigated the effects of topical sports cream containing Cymbopogon schoenanthus (CS) on acute recovery markers. This study aimed to examine the effects of the acute application of a TSC containing CS after exercise-induced muscle fatigue on acute recovery markers. Methods: Ten taekwondo athletes (male: 5, female: 5) participated in this study. In a crossover design with 2-week intervals, participants were randomly assigned to two clinical trial groups: TSC and placebo cream (PC). Isokinetic dynamometers were used to create exercise-induced muscle fatigue, and the subjects repeatedly performed external and internal shoulder rotations. TSC containing CS was applied to the shoulder muscles of the subjects after the exercise. Maximum voluntary isometric contraction, muscle pain, blood flow, and skin temperature were measured before, during, immediately after, 30 min after, and 60 min after exercise. Results: A significant interaction effect was found in blood flow between time and group (p = 0.032, ηp2 = 0.157). However, there was no statistically significant interaction effect between time and group for maximum voluntary isometric contraction (MVIC), muscle pain, and skin temperature (p > 0.05). Conclusions: Acute application of TSC containing CS is effective in increasing blood flow during the recovery period following exercise-induced muscle fatigue.

Cymbopogon schoenanthus; muscle fatigue; muscle pain; topical sports cream; recovery

[1] Gauche E, Couturier A, Lepers R, Michaut A, Rabita G, Hausswirth C. Neuromuscular fatigue following high versus lowintensity eccentric exercise of biceps brachii muscle. Journal of Electromyography & Kinesiology. 2009; 19: e481–e486.

[2] Shimokochi Y, Kuwano S, Yamaguchi T, Abutani H, Shima N. Effects of Wearing a Compression Garment during Night Sleep on Recovery from High-Intensity Eccentric-Concentric Quadri-ceps Muscle Fatigue. Journal of Strength and Conditioning Re-search. 2017; 31: 2816–2824.

[3] Mori H, Ohsawa H, Tanaka TH, Taniwaki E, Leisman G, Nishijo K. Effect of massage on blood flow and muscle fatigue following isometric lumbar exercise. Medical Science Monitor. 2004; 10: 173–178.

[4] Carpenter JE, Blasier RB, Pellizzon GG. The Effects of Muscle Fatigue on Shoulder Joint Position Sense. The American Journal of Sports Medicine. 1998; 26: 262–265.

[5] Mastaglia FL. The relationship between muscle pain and fatigue. Neuromuscular Disorders. 2012; 22: S178–S180.

[6] Cheung K, Hume PA, Maxwell L. Delayed Onset Muscle Soreness: treatment strategies and performance factors. Sports Medicine. 2003; 33: 145–164.

[7] Johar P, Grover V, Topp R, Behm DG. A comparison of topical menthol to ice on pain, evoked tetanic and voluntary force during delayed onset muscle soreness. International Journal of Sports Physical Therapy. 2012; 7: 314–322.

[8] Delextrat A, Calleja-González J, Hippocrate A, Clarke ND. Ef-fects of sports massage and intermittent cold-water immersion on recovery from matches by basketball players. Journal of Sports Sciences. 2013; 31: 11–19.

[9] Wiewelhove T, Schneider C, Döweling A, Hanakam F, Rasche C, Meyer T, et al. Effects of different recovery strategies follow-ing a half-marathon on fatigue markers in recreational runners. PLoS ONE. 2018; 13: e0207313.

[10] Costello JT, Baker PR, Minett GM, Bieuzen F, Stewart IB, Bleakley C. Whole-body cryotherapy (extreme cold air exposure) for preventing and treating muscle soreness after exercise in adults. Cochrane Database of Systematic Reviews. 2015; CD010789.

[11] Hendricks S, Hill H, Hollander SD, Lombard W, Parker R. Effects of foam rolling on performance and recovery: a systematic review of the literature to guide practitioners on the use of foam rolling. Journal of Bodywork and Movement Therapies. 2020; 24: 151–174.

[12] Malone JK, Blake C, Caulfield BM. Neuromuscular Electrical Stimulation during Recovery from Exercise: a systematic review. Journal of Strength and Conditioning Research. 2014; 28: 2478–2506.

[13] Manimmanakorn N, Manimmanakorn A, Boobphachart D, Thuwakum W, Laupattarakasem W, Hamlin MJ. Effects of Zingiber cassumunar (Plai cream) in the treatment of delayed onset muscle soreness. Journal of Integrative Medicine. 2016; 14: 114–120.

[14] Hill JM, Sumida KD. Acute Effect of 2 Topical Counterirritant Creams on Pain Induced by Delayed-Onset Muscle Soreness. Journal of Sport Rehabilitation. 2002; 11: 202–208.

[15] Al-Ghamdi S, Al-Ghamdi A, Shammah A. Inhibition of Calcium Oxalate Nephrotoxicity with Cymbopogon Schoenanthus (Al-Ethkher). Drug Metabolism Letters. 2007; 1: 241–244.

[16] Hashim GM, Almasaudi SB, Azhar E, Al Jaouni SK, Harakeh S. Biological activity of Cymbopogon schoenanthus essential oil. Saudi Journal of Biological Sciences. 2017; 24: 1458–1464.

[17] Ben Othman M, Han J, El Omri A, Ksouri R, Neffati M, Isoda H. Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in Tunisia. Evidence-Based Com-plementary & Alternative Medicine. 2013; 2013: 737401.

[18] Gomes E, Bernardo J, Barbosa M, Andrade PB, Valentão P, Lopes G. Ethnopharmacological use of Cymbopogon citratus (DC.) Stapf and Cymbopogon schoenanthus (L.) Spreng.: Anti-inflammatory potential of phenol-rich extracts: PS129. Porto Biomedical Journal. 2017; 2: 216–217.

[19] McLeay Y, Barnes MJ, Mundel T, Hurst SM, Hurst RD, Stannard SR. Effect of New Zealand blueberry consumption on recovery from eccentric exercise-induced muscle damage. Journal of the International Society of Sports Nutrition. 2012; 9: 19.

[20] Dashottar A. Acute effects of softball pitching to fatigue on the glenohumeral internal rotation range of motion. Physiotherapy

- The Journal of Indian Association of Physiotherapists. 2019; 13: 23–29.

[21] Joshi M, Thigpen CA, Bunn K, Karas SG, Padua DA. Shoulder External Rotation Fatigue and Scapular Muscle Activation and Kinematics in Overhead Athletes. Journal of Athletic Training. 2011; 46: 349–357.

[22] Roy J, Ma B, MacDermid JC, Woodhouse LJ. Shoulder mus-cle endurance: the development of a standardized and reliable protocol. Sports Medicine, Arthroscopy, Rehabilitation, Ther-apy and Technology. 2011; 3: 1.

[23] Kanda K, Sugama K, Hayashida H, Sakuma J, Kawakami Y, Miura S, et al. Eccentric exercise-induced delayed-onset muscle soreness and changes in markers of muscle damage and inflam-mation. Exercise Immunology Review. 2013; 19: 72–85.

[24] Romero-Moraleda B, González-García J, Cuéllar-Rayo Á, Balsalobre-Fernández C, Muñoz-García D, Morencos E. Effects of Vibration and Non-Vibration Foam Rolling on Recovery after Exercise with Induced Muscle Damage. Journal of Sports Sci-ence & Medicine. 2019; 18: 172–180.

[25] Alghadir AH, Answer S, Iqbal A, Iqbal ZA. Test-retest relia-bility, validity, and minimum detectable change of visual ana-log, numerical rating, and verbal rating scales for measurement of osteoarthritic knee pain. Journal of Pain Research. 2018; 11: 851–856.

[26] Bijur PE, Silver W, Gallagher EJ. Reliability of the Visual Ana-log Scale for Measurement of Acute Pain. Academic Emergency Medicine. 2001; 8: 1153–1157.

[27] Tripathi A, Obata Y, Ruzankin P, Askaryar N, Berkowitz DE, Steppan J, et al. A Pulse Wave Velocity Based Method to Assess the Mean Arterial Blood Pressure Limits of Autoregulation in Peripheral Arteries. Frontiers in Physiology. 2017; 8: 855.

[28] Schörkmaier T, Wahl Y, Brinkmann C, Bloch W, Wahl P. No Influence of Nonivamide-nicoboxil on the Peak Power Out-put in Competitive Sportsmen. International Journal of Sports Medicine. 2021; 42: 1092–1097.

[29] Petrofsky J, Laymon M, Khowailed I, Lee H. Synergistic Effects of Continuous Low Level Heat Wraps and Vitamins in Improv-ing Balance and Gait in Adults. International Journal for Vitamin and Nutrition Research. 2016; 86: 152–160.

[30] Kim K, Monroe JC, Gavin TP, Roseguini BT. Local Heat Therapy to Accelerate Recovery after Exercise-Induced Muscle Damage. Exercise and Sport Sciences Reviews. 2020; 48: 163–169.

[31] McGorm H, Roberts LA, Coombes JS, Peake JM. Turning up the Heat: an Evaluation of the Evidence for Heating to Promote Ex-ercise Recovery, Muscle Rehabilitation and Adaptation. Sports Medicine. 2018; 48: 1311–1328.

[32] Kano Y, Padilla DJ, Behnke BJ, Hageman KS, Musch TI, Poole DC. Effects of eccentric exercise on microcirculation and mi-crovascular oxygen pressures in rat spinotrapezius muscle. Jour-nal of Applied Physiology. 2005; 99: 1516–1522.

[33] Zeng, C, Luo, G, Xu, S, Li, Y. The Application of DOMS Mech-anism and Prevention in Physical Education and Training. Jour-nal of Healthcare Engineering. 2022; 2022: 9654919.

[34] Craighead DH, Alexander LM. Topical menthol increases cuta-neous blood flow. Microvascular Research. 2016; 107: 39–45.

[35] Gillis DJ, Vellante A, Gallo JA, D’Amico AP. Influence of Men-thol on Recovery from Exercise-Induced Muscle Damage. Jour-nal of Strength and Conditioning Research. 2020; 34: 451–462.