Article Menu

Export Article

More by Authors Links

Article Data

  • Views 3513
  • Dowloads 230

Case Report

Open Access

Prostate leiomyosarcoma treatment using three-dimensional reconstruction: a case report and literature review

  • Zhu-Nan Xu1,†
  • Tong Cai1,†
  • Zhong-Bao Zhou2
  • Ji-Tao Wu3
  • Zhen-Li Gao4

1Binzhou Medical University, Yantai, 264003 Shandong, P. R. China and Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, 264000 Shandong, P. R. China

2Department of Urology, Beijing TianTan Hospital, Capital Medical University. No.119 South 4th Ring West Road, Fengtai District, 100070 Beijing, P. R. China

3Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, 264000 Shandong, P. R. China

4Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, 264000 Shandong, P. R. China and Binzhou Medical University, Yantai, 264003 Shandong, P. R. China

DOI: 10.31083/jomh.2021.018 Vol.17,Issue 2,April 2021 pp.148-153

Published: 08 April 2021

*Corresponding Author(s): Zhen-Li Gao E-mail: xzn13791280550@163.com

† These authors contributed equally.

PDF (11.82 MB) View Full-text

Abstract

Background: Prostate sarcoma is a malignant tumor from the prostate stroma. However, its pathogenesis is unknown. This is a rare type of prostate tumor.

Case Presentation: A rare case of prostate leiomyosarcoma has been described. A 55-year-old prostate leiomyosarcoma patient who suffered from progressive dysuria and frequent urination for half a year was examined. Pathology, immunohistochemical staining, and laparoscopic radical prostatectomy were performed using three-dimensional (3D) reconstruction to diagnose prostate leiomyosarcoma. The patient did not receive adjuvant therapy after the operation. Final pathology was used to confirm prostate leiomyosarcoma. After one year of follow-up, the patient regularly underwent a digital rectal examination and abdominal MRI. However, no tumor recurrence or metastasis was found.

Discussion: We discussed diagnosis and treatment of prostate leiomyosarcoma and reviewd literatures.

Conclusion: Prostate leiomyosarcoma is a rare special type of prostate tumor, and its diagnosis is mainly based on pathological features. Radical excision is the primary treatment for prostate leiomyosarcoma. The 3D reconstruction is essential in the surgery because it can determine the size of the tumor and its relationship to the surrounding tissue. A postoperative adjuvant therapy can also be performed.

Keywords

Prostate leiomyosarcoma; diagnosis; treatment; three-dimensional reconstruction; case report

Cite and Share

Zhu-Nan Xu,Tong Cai,Zhong-Bao Zhou,Ji-Tao Wu,Zhen-Li Gao. Prostate leiomyosarcoma treatment using three-dimensional reconstruction: a case report and literature review. Journal of Men's Health. 2021. 17(2);148-153.

URL:

https://www.jomh.org/articles/10.31083/jomh.2021.018

References

[1] Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA: A Cancer Journal for Clinicians. 2013; 63: 11-30.

[2] Rojas-Jiménez A, Otero-Garcia M, Mateos-Martin A. Stromal pro-static sarcoma: a rare tumor with rare clinical and imaging presen-tation. Journal of Radiology Case Reports. 2013; 7: 24-31.

[3] Riley DS, Barber MS, Kienle GS, Aronson JK, von Schoen-Angerer T, Tugwell P, et al. CARE guidelines for case reports: explanation and elaboration document. Journal of Clinical Epidemiology. 2017; 89: 218- 235.

[4] Schubert C, van Langeveld MC, Donoso LA. Innovations in 3D printing: a 3D overview from optics to organs. British Journal of Ophthalmology. 2014; 98: 159-161.

[5] Bird J. Exploring the 3D printing opportunity. The Financial Times. 2012.

[6] George A. 3-D printed car is as strong as steel, half the weight, and nearing production. Wired. 2013. Available at: http: //www.wired.com/autopia/2013/02/3d-printed-car/

(Accessed: 27 February 2015).

[7] Marks P. 3D printing: the world’s first printed plane. New Scientist. 2011. Available at: http://www.newscientist.com/article/dn20737-3d-printing-the-worlds-first-printed-plane.html#Ux4SLx_LI7x (Accessed: 01 August 2014).

[8] Greenberg A. Meet the ‘liberator’: test-firing the world’s first fully 3D-printed gun. Forbes. 2013. Available at: http://www.forbes.com/sites/andygreenberg/2013/05/05/meet-the-liberator-test-firing-the-worlds-first-fully-3d-printed-gun/(Accessed: 14 June 2015).

[9] Macguire E. Dutch architects build world’s first 3D printed house. CNN. 2015. Available at: http://edition.cnn.com/2014/04/ 13/business/3d-printed-house-amsterdam/ (Accessed: 14 April 2015).

[10] Mondaini N, Palli D, Saieva C, Nesi G, Franchi A, Ponchietti R, et al. Clinical characteristics and overall survival in genitourinary sarcomas treated with curative intent: a multicenter study. European Urology. 2005; 47: 468-473.

[11] Humphrey PA. Angiosarcoma of the prostate. The Journal of Urology. 2012; 187: 684-685.

[12] Ren FY, Lu JP, Wang J, Ye JJ, Shao CW, Wang MJ. Adult prostate sarcoma: radiological-clinical correlation. Clinical Radiology. 2009; 64: 171-177.

[13] Boyle H, Fléchon A, Droz JP. Treatment of uncommon malignant tumours of the bladder. Current Opinion in Urology. 2011; 21: 309-314.

[14] Zazzara M, Divenuto L, Scarcia M, Cardo G, Maselli FP, Ludovico GM. Leiomyosarcoma of prostate: case report and literature review. Urology Case Reports. 2017; 17: 4-6.

[15] Vandoros GP, Manolidis T, Karamouzis MV, Gkermpesi M, Lam-bropoulou M, Papatsoris AG, et al. Leiomyosarcoma of the prostate: case report and review of 54 previously published cases. Sarcoma. 2008; 2008: 458709.

[16] Kaufman JJ, Berneike RR. Leiomyoma of the prostate. The Journal of Urology. 1951; 65: 297-310.

[17] Dotan ZA, Tal R, Golijanin D, Snyder ME, Antonescu C, Brennan MF, et al. Adult genitourinary sarcoma: the 25-year memorial Sloan-Kettering experience. Journal of Urology. 2006; 176: 2033-2039.

[18] Janet NL, May A, Akins RS. Sarcoma of the prostate: a single institutional review. American Journal of Clinical Oncology. 2009; 32: 27-29.

[19] Miedler JD, Maclennan GT. Leiomyosarcoma of the prostate. The Journal of Urology. 2007; 178: 668.

[20] Hossain D, Meiers I, Qian J, MacLennan GT, Bostwick DG. Prostatic leiomyoma with atypia: follow-up study of 10 cases. Annals of Diagnostic Pathology. 2008; 12: 328-332.

[21] Sexton WJ, Lance RE, Reyes AO, Pisters PWT, Tu S, Pisters LL. Adult prostate sarcoma: the M. D. Anderson Cancer Center experience. Journal of Urology. 2001; 166: 521-525.

[22] Cheville JC, Dundore PA, Nascimento AG, Meneses M, Kleer E, Farrow GM, et al. Leiomyosarcoma of the prostate. Report of 23 cases. Cancer. 1995; 76: 1422-1427.

[23] Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Annals of Surgical Oncology. 2010; 17: 1471-1474.

[24] Clark MA, Fisher C, Judson I, Thomas JM. Soft-tissue sarcomas in adults. The New England Journal of Medicine. 2005; 353: 701-711.

[25] Lin M, Hsiao H. Promising effects of pazopanib with radiation on an advanced prostate leiomyosarcoma after failure of systemic chemotherapy. The Kaohsiung Journal of Medical Sciences. 2019; 35: 317- 318.

[26] Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. Journal of Clinical Oncology. 2003; 21: 4342-4349.

[27] Porpiglia F, Bertolo R, Checcucci E, Amparore D, Autorino R, Das-gupta P, et al. Development and validation of 3D printed virtual models for robot-assisted radical prostatectomy and partial nephrectomy: urologists’ and patients’ perception. World Journal of Urology. 2018; 36: 201-207.

Submission Turnaround Time

Top