Sex-speciﬁc in the relationship between hyperuricemia and pulse pressure in non-diabetic Korean adults: the 2017 Korean National Health and Nutrition Examination Survey
1Department of Radiological Science, Hanlyo University, 57764 Gwangyangsi, South Korea
2Department of Emergency Medical Technology, Gwangju Health University, 62287 Gwangsan-gu, South Korea
3Department of Radiology, Cheomdan Hospital, 62274 Gwangsan-gu, South Korea
4Department of global Medical Beauty, Konyang University, 32992 Nonsan-si, South Korea
5Department of Biomedical Laboratory Science, Wonkwang Health Science University, 54538 Iksan-si, South Korea
DOI: 10.31083/jomh.2021.064 Vol.18,Issue 1,January 2022 pp.1-8
Submitted: 12 March 2021 Accepted: 23 March 2021
Published: 31 January 2022
*Corresponding Author(s): Hyun Yoon E-mail: email@example.com
Background and objective: The present study assesses the relationship between hyperuricemia and pulse pressure (PP) in non-diabetic Korean adults.
Material and methods: Data from 5122 subjects (2251 men and 2871 women) in the seventh Korean National Health and Nutrition Examination Survey (KNHANES VII-2, 2017) were analyzed.
Results: Systolic blood pressure (SBP) and PP were signiﬁcant factors determining the odds ratios (ORs) for hyperuricemia (uric acid ≥7.0 mg/dL in men or ≥6.0 mg/dL in women) in men and the overall population. In women, SBP, diastolic blood pressure (DBP), and PP were not signiﬁcant factors determining the OR for hyperuricemia. After adjusting for related variables, the OR of hyperuricemia was signiﬁcantly higher in the high PP group (PP >60.0 mmHg) for men (OR, 1.760; 95% conﬁdence interval [CI], 1.152--2.688) and the overall population (OR, 1.557; 95% CI, 1.132--2.140) compared with the normal PP group, but this trend was not seen in women (OR, 1.060; 95% CI, 0.646--1.740).
Conclusions: Hyperuricemia was positively associated with PP in non-diabetic Korean men but not in women.
Uric acid; Pulse pressure; Systolic blood pressure; Gender difference; Non-diabetic population
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