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LIFESTYLE INTERVENTION FOR PROMOTING PHYSICAL ACTIVITY IN PROSTATE CANCER PATIENTS WITH ANDROGEN DEPRIVATION THERAPY

  • Jung Jun Lim1
  • Yeon Soo Kim1,2
  • Hong Yong Choi3
  • Kyu Shik Kim3
  • Hong Sang Moon4
  • Hyung Joon Park5
  • Jae Hang Shim5

1Department of Physical Education, College of Education, Seoul National University, Seoul, Republic of Korea

2Institute of Sport Science, Seoul National University, Seoul, Republic of Korea

3Department of Urology, Hanyang University Guri Hospital, Guri-si, Republic of Korea

4Department of Urology, Hanyang University College of Medicine, Seoul, Republic of Korea

5Department of Anesthesiology and Pain Medicine, Hanyang University College of Medicine, Guri Hospital, Republic of Korea

DOI: 10.31083/jomh.v16i4.265 Vol.16,Issue 4,October 2020 pp.54-64

Published: 01 October 2020

*Corresponding Author(s): Hong Sang Moon E-mail: moonuro@hanyang.ac.kr

Abstract

Background and objective

Despite the awareness of the important roles of physical activity (PA), the majority of cancer survivors fail to meet PA guidelines due to a lack of access to facilities or motivation. The purpose of this study is to examine the effectiveness of lifestyle intervention in prostate cancer (PC) patients receiving androgen deprivation therapy (ADT).

Material and methods

A total of 23 PC patients (aged 75.26 ± 6.9 years) receiving ADT at least 3 months were randomized into an intervention group (n=12) and a control group (n=11). The intervention group received lifestyle interven-tion in the form of education program. Levels of PA, body composition, physical function, disease-specific quality of life (QoL), and fatigue were assessed before and after the 12-week intervention.

Results

The intervention group showed improvements in the level of PA (step count: p=0.028, moderate to vig-orous PA: p=0.013) compared with the control group. Thigh circumference (p=0.002), physical function (grip strength: p=0.034; knee extensor: p=0.004, up and go: p=0.001; 2-min step: p=0.001), QoL (p<0.001), and fatigue (p=0.001) were also improved compared with the control group. There were no adverse events during the lifestyle intervention period.

Conclusion

The 12-week lifestyle intervention program appears to be a promising strategy to increase the PA and mit-igate the side effects of ADT for PC patients.

Keywords

androgen deprivation therapy; lifestyle intervention; prostate cancer; side effects

Cite and Share

Jung Jun Lim,Yeon Soo Kim,Hong Yong Choi,Kyu Shik Kim,Hong Sang Moon,Hyung Joon Park,Jae Hang Shim. LIFESTYLE INTERVENTION FOR PROMOTING PHYSICAL ACTIVITY IN PROSTATE CANCER PATIENTS WITH ANDROGEN DEPRIVATION THERAPY. Journal of Men's Health. 2020. 16(4);54-64.

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