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Open Access Special Issue

Seasonal variations in vascular endothelial function and physical activity in men

  • Hiroto Honda1,*,
  • Makoto Igaki2

1Faculty of Rehabilitation, Shijonawate Gakuen University, 574-0011 Daito, Japan

2Department of Rehabilitation, Toyooka Hospital, 668-8501 Toyooka, Japan

DOI: 10.31083/jomh.2021.136 Vol.18,Issue 2,February 2022 pp.1-8

Submitted: 24 August 2021 Accepted: 19 August 2021

Published: 28 February 2022

(This article belongs to the Special Issue Lifestyle modifications for men with hypertension)

*Corresponding Author(s): Hiroto Honda E-mail:


Vascular endothelial function, which plays an important independent role in the onset of cardiovascular disease, often changes seasonally, with functional deterioration generally occurring during the winter. Physical activity is necessary for preventing cardiovascular disease and all-cause mortality, as it improves vascular endothelial and metabolic function; however, the amount of physical activity an individual gets also varies with the seasons. Changes in physical activity may induce seasonal variations in vascular endothelial function, although this hypothesis remains unconfirmed. An individual's sex can also affect their vascular endothelial function, habitual physical activity, and hormonal and metabolic function. Men have a higher risk of cardiovascular disease compared to women; therefore, clarifying the impact of physical activity on vascular endothelial function and its seasonality is important for managing men's health. The purpose of this article is to review the association between seasonal variations in vascular endothelial function and physical activity in men.


Vascular endothelial function; Physical activity; Seasonal variation; Hormonal function; Metabolic function

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Hiroto Honda,Makoto Igaki. Seasonal variations in vascular endothelial function and physical activity in men. Journal of Men's Health. 2022. 18(2);1-8.


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